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Mixing Propofol with benzodiazepines is normal to maxime the "effect", however he might have been given too much benzodiazepines since it already existed in his blood system. But the coroner stated that his Michael died due to acute intoxication of propofol which would mean that he was given too much Propofol and not too much benzodiazepines.
thankyou for your inputs but no one is getting my point i guess i was saying ok letrs say he was giving him like everynite , where was the cannula ( the tube inserted in a body to administer in the body) it shold be in the arm if there was an open iv according to dr klien that mj has had it on front of his arm? did anyone notice it and second point is if its there in the arm no one can move it dancing is just not possible because it hurts alot u know
Quote from: "Alem (Thetruth)"Mixing Propofol with benzodiazepines is normal to maxime the "effect", however he might have been given too much benzodiazepines since it already existed in his blood system. But the coroner stated that his Michael died due to acute intoxication of propofol which would mean that he was given too much Propofol and not too much benzodiazepines.Propofol dosage reported in Michael Jackson case is low, experts sayDr. Conrad Murray told police he injected 25 milligrams the night the pop star died. Experts say that dose would have little effect on an average patient, and possibly no effect on a regular user.August 27, 2009|Kimi YoshinoIf Michael Jackson died from lethal levels of the powerful anesthetic propofol, then he must have been injected with much more of the drug than his personal physician reportedly told police he gave the pop star, medical experts said.According to court records unsealed in Houston on Monday, Dr. Conrad Murray told police that he had been giving Jackson 50 milligrams of propofol each night for six weeks. In a three-hour interview with police two days after Jackson's death, Murray said he had been trying to wean the singer off the anesthetic and, on the day of his death, gave him a combination of other sedatives before succumbing to Jackson's demands for propofol.Murray then gave Jackson 25 milligrams of propofol, according to the documents. But those amounts -- 25 and 50 milligrams -- are far below the dosage required to anesthetize someone and keep them asleep, several experts said."It doesn't make any sense," said Dr. John Dombrowski of the American Society of Anesthesiologists. "I cannot believe that was the number that was given. Such a small amount won't tip anyone over in terms of respiratory depression."What's more likely, Dombrowski said, is that the numbers in the documents are somehow in error. Murray might not have provided an infusion rate, such as 25 milligrams every few minutes, or police might not have understood the medical terminology, Dombrowski said.The preliminary toxicology reports cited in the court records said that "lethal levels" of propofol were found in Jackson's blood. Final autopsy and toxicology reports have yet to be released by the Los Angeles County coroner's office.Murray has said through his attorney that he believes nothing he administered should have led to Jackson's death. His attorney, Ed Chernoff, said Murray answered the detectives' questions truthfully.The medical experts said that if the propofol dosage were higher and combined with other medications, it could have led to an overdose.Dr. Scott Engwall, vice chair of anesthesiology at UC Irvine's School of Medicine, said that for an average person without a high tolerance to drugs, 50 milligrams of propofol might be enough to make him or her doze off for five or 10 minutes. Someone like Jackson, who had been using it nightly for six weeks, according to Murray's testimony, might close his eyes briefly -- or it might not work at all, Engwall and other doctors said."I think . . . there is some part of this picture we still do not know," Engwall said.http://articles.latimes.com/2009/aug/27 ... son-drug27So how does someone die from acute propofol intoxication when they haven't been administered enough of the drug to have any significant effect on the person. If Dr. Murray is lying about the amount of propofol he administered why? He claims he was trying to wean MJ off propofol hence the low dosage. There is something not right about this entire scenario.
Quote from: "mjj_fan"thankyou for your inputs but no one is getting my point i guess i was saying ok letrs say he was giving him like everynite , where was the cannula ( the tube inserted in a body to administer in the body) it shold be in the arm if there was an open iv according to dr klien that mj has had it on front of his arm? did anyone notice it and second point is if its there in the arm no one can move it dancing is just not possible because it hurts alot u knowI remember when I had an IV placed in my hand, they told me not to move it. To keep it as still as possible. It would be uncomfortable to have something like that in your limb. Then take into account vigorous dancing, it would be excurciating and likely cause damaged.Thanks for all the information everyone! :D
meth patch is methyl phenidate which is different catagory of drug used for sleep disorder but i havent heard dr klein saying mj used it infact i read he said i warn micheal of propofol when he used it during history tour
@ Gem . you are rite when veins are collapsed any prominent vein we ask the staff to maintain for iv lines specially for very sick terminal patients but they are Not the first choice to place them and where no veins are seen we prefer to perform a venous cut down in those cases but again in serious patients at ICU i think you might have seen it on dorsum of foot( i.e on the front)_ or at the side of foot and in children at the head ,other than that in emergency a tube in introduced in the neck if forearm veins are not visible
@ lisa , you wrote what exactly i wanted to convey to others thanks for making that easier for me ,thats what i was trying to say maintaining an Iv line aint like pricking with a a needle and thats all, you cant place the cannula over the same place again n again, sometimes the blood oozes out and the vein eventually collapsed one has to be very careful to maintain Iv lines specially in emergency cases
