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Dr. Murray's Defense - Jackson Killed HimselfPosted Apr 4th 2010 4:00AM by TMZ StaffTMZ has learned Dr. Conrad Murray's legal defense is that Michael Jackson gave himself the fatal dose of Propofol.Multiple sources familiar with the strategy tell TMZ the defense argument goes like this:- At around 10:50 AM, Dr. Murray gave Jackson 25 mg of Propofol from a 20 ml bottle -- that's only about 1/8 of the bottle.- The dose Dr. Murray administered would keep someone asleep for only 5 to 10 minutes, But the Propofol, along with the Ativan and Versed that was already in MJ's system, had a synergistic effect that put Jackson to sleep for a longer period of time.- For the next hour, Dr. Murray stayed in the room and was on the phone for much of the time. Dr. Murray didn't leave the room to make the calls because MJ liked activity in the room, regularly sleeping with the lights on and cartoons blaring on the TV.- At around noon, Dr. Murray left the room for approximately two minutes to go to the bathroom. While he was gone, the defense believes Jackson suddenly awakened and was frustrated he had spent nearly 9 hours trying in vain to sleep. The defense theory -- Jackson took the 20 ml bottle of Propofol and self-injected the remaining contents through the IV, causing a massive overdose that stopped his heart.- Dr. Murray walked back in the room and saw Jackson with his eyes open and pupils dilated. Dr. Murray dropped the phone (he was speaking with his girlfriend) and began administering CPR.The defense will argue Michael Jackson was a long-time Propofol addict -- something TMZ first reported shortly after the singer's death. As one source said, Jackson liked the sensation of Propofol being administered by IV, adding, "Michael liked to push it."L.A. County Coroner's investigators took a picture in the room, showing an empty Propofol bottle on the floor, underneath the nightstand by Jackson's bed. The defense will argue Jackson grabbed the bottle from the nightstand, injected himself and then dropped the bottle.Remember, law enforcement believes Dr. Murray hid bottles of Propofol before paramedics arrived. The defense will argue ... if Dr. Murray was really hiding Propofol, he would have removed the empty bottle under the nightstand that caused Jackson's death.Ed Chernoff, Murray's attorney, could not be reached for comment.Read more: You are not allowed to view links. Register or Login
Nice how TMZ know what the strategy of Doc Murray's defense will be:"The defense will argue Michael Jackson was a long-time Propofol addict"- we said this since June that MJ as drug addict MUST be the logical and only consequence of the plot..."As one source said, Jackson liked the sensation of Propofol being administered by IV, adding, "Michael liked to push it." - Propofol hurts the veins during injection, this is not fun stuff.Oh - by the way, I ran over this VERY interesting description of veterinary use of Propofol and I bet you will join me in laughing:A cat can take a one-time injection of up to 8 mg / kg (translating in a total body weight of 25 kg / 55 lbs that could be injected with the content of a 20 ml ampule containing 10 mg/ml of the drug (=200 mg)).A cat can take a constant infusion of 0.1 - 0.8 mg/kg/min (translating into a 5 or 40 mg infusion per minute given MJ's body weight of 117 lbs / 50 kg thus an infusion duration of 40 or 5 minutes.So if MJ was first injected with 25 mg, this would have been sufficient for putting a kitten of 3.1 kg / 6.9 lbs. to sleep. Injection of the remaining 175 mg in one shot would have been sufficient to put a dog of 21.9 kg / 48.2 lbs to sleep.MJ was reported to have weighed 117 lbs. / 50 kg.TMZ states in today's article again to get 25 mg out of 20 ml with the first IV application and a deadly dosis with the rest... don't let them fool you around Propofol Injection 10 mg/ml in 20 ml ampules - results in 200 mg in a 20 ml ampule; We discussed Propofol many times - this is a veterinary point of view on dosage:You are not allowed to view links. Register or Login[...][Doses - Dogs & Cats:a) As a single injection (25% of the calculated dose every 30 seconds until desired effect):For healthy, unpremedicated animal: 6 mg/kg IVFor healthy, premedicated animal: After tranquilizer (e.g., acepromazine) = 4 mg/kg IV; After sedative (e.g., xylazine, opioids) = 3 mg/kg IV As a constant infusion:For sedation only: 0.1 mg/kg/minute For minor surgery: 0.6 mg/kg/min, or 1 ml (10 mg) per minute per 12-25 kg of body weight (Robinson, Sanderson et al. 1993)b) 4 - 8 mg/kg IV (Hubbell 1994)c) 6 mg/kg IV; in healthy animals 25% of the calculated dose is administered every 30 seconds until intubation is possible. After induction, duration of anesthesia is only 2.5 - 9.4 minutes. Maintenance anesthesia obtained using either inhalational agents or a continuous infusion of propofol at approximately 0.4 mg/kg/minute. If anesthesia appears inadequate, a small bolus of 1 mg/kg followed by an increase in the infusion rate by 25%. If infusion is too deep, discontinue infusion until suitable anesthesia level is achieved. An infusion dose of 0.1 mg/kg/min appears to be suitable dose for sedation in the dog. (Ilkiw 1992)d) As an induction agent for halothane or isoflurane anesthesia: 6.6 mg/kg IV given over 60 seconds to unpredmedicated dogs. Best achieved by early intubation and administration of the inhalant following propofol induction. (Bufalari, Miller et al. 1998)[...]Dosage Forms/Preparations/FDA Approval Status/Withholding Times -Veterinary-Approved Products:Propofol Injectable 10 mg/ml in 20 ml (single use) amps & vials; Rapinovet® (Schering); PropoFlo ® (Abbott) (Rx). Approved for use in dogs.Human-Approved Products:Propofol Injection 10 mg/ml in 20 ml ampules and 50 & 100 ml vials for infusion; Diprivan® (Zeneca); (Rx)[...]
Started by mjlovebug TIAI ~ 2010
Started by mjlovebug « 1 2 » TIAI ~ 2010
Started by MJEnjoyYourself TIAI ~ 2010
